Controlled ploidy reduction of pluripotent 4n cells generates 2n cells during mouse embryo development
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چکیده
منابع مشابه
Fate of tetraploid cells in 4n↔2n chimeric mouse blastocysts
Previous studies have shown that tetraploid (4n) cells rarely contribute to the derivatives of the epiblast lineage of mid-gestation 4n<-->2n mouse chimeras. The aim of the present study was to determine when and how 4n cells were excluded from the epiblast lineage of such chimeras. The contributions of GFP-positive cells to different tissues of 4n<-->2n chimeric blastocysts labelled with tauGF...
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ژورنال
عنوان ژورنال: Science Advances
سال: 2019
ISSN: 2375-2548
DOI: 10.1126/sciadv.aax4199